Lyon, last season's runners-up, commenced their Women's Champions League campaign with an emphatic 8-0 victory over Servette. Marie-Antoinette Katoto netted a hat-trick, supported by a double from Melchie Dumornay, an own goal from Laia Balleste, another from Magdalena Sobal, and a late strike by Ines Benyahia. Meanwhile, defending champions Barcelona secured a 5-2 win against Paris FC, featuring two goals from Ewa Pajor, alongside strikes from Kerolin, Clara Serrajordi, and Caroline Graham Hansen. Notably, Alexia Putellas transferred to London City Lionesses during the summer.

Other results included Chelsea's 1-0 triumph over Austria Vienna, with Wieka Kaptein scoring, and a goalless draw between OH Leuven and Roma. Manchester City also fought back for a 2-2 draw against Bayern Munich, while Arsenal edged HB Koge 1-0.